You are studying the effects of a compound on the respiratory activity of isolated mitochondria. Your experiments demonstrate that oxygen consumption is normal when pyruvate and malate are added. Oxygen consumption is also seen to be normal when succinate is added. However, you find that the production of ATP is severely impaired in the presence of pyruvate/malate or succinate when the compound is added to the reaction.
These results most closely resemble the effects that would be seen by the addition of which of the following inhibitors of oxidative phosphorylation?